Journal of Korean Society of Health-System Pharmacists

Indexed in /covered by CAS, KoreaScience & DOI/Crossref:eISSN    pISSN

Table. 1.

Table. 1.

Prescription practices of contraindicated drug-drug interaction

Inpatient(n=19,996) Outpatient(n=2,543) Total(n=22,539)
n (%)
Between prescriptions/within one prescription
Between prescriptions 12,972 (64.9) 1,407 (55.3) 14,379 (63.8)
Within one prescription 7,024 (35.1) 1,136 (44.7) 8,160 (36.2)
The number of alert per 10,000 prescriptions* 60.8 18.8
The number of drug combinations
Total 176
Between prescriptions 165
Within one prescription 118
Inpatient 123
Outpatient 135
Sex
Male 10,167 (50.8) 1,724 (67.8) 11,891 (52.8)
Female 9,829 (49.2) 819 (32.2) 10,648 (47.2)
Age, mean ± SD§ 59.2 ± 20.0 60.7 ± 16.0 59.4 ± 16.0
≤ 19 831 (4.2) 36 (1.4) 867 (3.8)
20 ~ 29 916 (4.6) 81 (3.2) 997 (4.4)
30 ~ 39 1,891 (9.5) 164 (6.4) 2,055 (9.1)
40 ~ 49 2,067 (10.3) 291 (11.4) 2,358 (10.5)
50 ~ 59 3,000 (15.0) 418 (16.4) 3,418 (15.2)
60 ~ 69 4,151 (20.8) 787 (30.9) 4,938 (21.9)
70 ~ 79 4,506 (22.5) 568 (22.3) 5,074 (22.5)
≥ 80 2,634 (13.2) 198 (7.8) 2,832 (12.6)
Medical department
Cardiovascular surgery 2,089 (10.4) 11.0 (0.4) 2,100 (9.3)
Cardiology 1,741 (8.7) 279 (11.0) 2,020 (9.0)
Hemato-oncology 1,926 (9.6) 79 (3.1) 2,005 (8.9)
General surgery 1,962 (9.8) 23 (0.9) 1,985 (8.8)
Plastic surgery 1,799 (9.0) 11 (0.4) 1,810 (8.0)
Neurosurgery 1,707 (8.5) 44 (1.7) 1,751 (7.8)
Pulmonology 1,368 (6.8) 52 (2.0) 1,420 (6.3)
Obstetrics and Gynecology 1,270 (6.4) 6 (0.2) 1,276 (5.7)
Oncology 1,202 (6.0) 71 (2.8) 1,273 (5.6)
Nephrology 639 (3.2) 558 (21.9) 1,197 (5.3)
Gastroenterology 867 (4.3) 61 (2.4) 928 (4.1)
Orthopedic Surgery 865 (4.3) 8 (0.3) 873 (3.9)
Urology 155 (0.8) 633 (24.9) 788 (3.5)
Infectious diseases 685 (3.4) 54 (2.1) 739 (3.3)
Pediatrics 445 (2.2) 30 (1.2) 475 (2.1)
Etc. 1,276 (6.4) 623 (24.5) 1,899 (8.4)

*In 2019, the total number of prescriptions was 3,286,189 for inpatients and 1,353,374 for outpatients

107 drug combinations occurred both between prescriptions and within one prescription

82 drug combinations occurred both inpatient and outpatient

§ SD : standard deviation

J. Kor. Soc. Health-syst. Pharm. 2021;38:291-305 https://doi.org/10.32429/jkshp.2021.38.3.001
© 2021 J. Kor. Soc. Health-syst. Pharm.